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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
13.64
Human Site:
S578
Identified Species:
30
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
S578
G
E
L
E
D
Y
M
S
D
R
V
Q
F
V
I
Chimpanzee
Pan troglodytes
XP_512717
596
65689
S541
G
E
L
E
D
Y
M
S
D
R
V
Q
F
V
I
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
D587
E
D
S
G
D
T
E
D
E
L
R
R
V
A
E
Dog
Lupus familis
XP_533653
654
71801
S599
G
E
L
E
D
Y
M
S
D
R
V
Q
F
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
N576
G
E
L
E
D
Y
M
N
E
R
V
Q
F
V
I
Rat
Rattus norvegicus
Q9ESZ0
631
68817
S576
G
E
L
E
D
Y
M
S
D
R
V
Q
F
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
L495
C
R
G
C
C
D
A
L
R
G
M
R
G
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
N596
G
E
L
E
E
Y
M
N
E
K
V
Q
F
V
I
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
G555
R
Y
I
I
A
F
N
G
A
V
E
D
Y
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
E541
K
D
D
V
A
M
L
E
D
S
K
L
T
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
D457
G
L
I
E
N
Y
M
D
E
S
V
N
Y
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
6.6
100
N.A.
86.6
100
N.A.
0
N.A.
73.3
0
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
13.3
N.A.
100
26.6
N.A.
26.6
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
10
0
10
0
0
0
0
19
10
% A
% Cys:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
10
0
55
10
0
19
46
0
0
10
0
0
0
% D
% Glu:
10
55
0
64
10
0
10
10
37
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
55
0
0
% F
% Gly:
64
0
10
10
0
0
0
10
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
64
% I
% Lys:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
10
55
0
0
0
10
10
0
10
0
10
0
0
10
% L
% Met:
0
0
0
0
0
10
64
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
10
19
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% Q
% Arg:
10
10
0
0
0
0
0
0
10
46
10
19
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
37
0
19
0
0
0
10
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
10
64
0
10
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
64
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _